Notes
Slide Show
Outline
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Rash Decisions in Hot Kids
Bernard A. Cohen, M.D.
Johns Hopkins Children’s Center
dermatlas.org
  • How to get started
  • Systematic evaluation
  • Algorithms
  • Try your luck at dermatlas.org
  • When all else fails ask your friendly neighborhood dermatologist
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Clues-the setting
  • Office, OPD
  • Inpatient
  • NICU
  • PICU
  • Post surgery
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More clues-past medical hx
  • Medical disorders
  • Drug exposure
  • Time of year
  • Geography
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…and the age of the patient
  • Variable morphology of the rash
  • Variable course
  • Immunologic parameters
  • Variable exposure/susceptibility to infection
  • (neonate <2 yrs <5 yrs <18 yrs)
  • Variable incidence of disease
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Clinical Check List
  • Mucous membranes
  • Palms/soles
  • Nails
  • Scalp
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SJS
v
 SSS
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DDx for strawberry tongue?
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…clues in the scalp
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…copper pennies on the soles
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… and Beau lines?
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…nail dystrophy
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Course of skin findings
  • How long?
  • Progression?
  • Pruritus?
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Systematic Approach to Clinical Findings
  • Pattern
  • Organization
  • Depth
  • Morphology
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Papulosquamous?
  • Itchyà


  • Acralà


  • PR patternà
  • Intertriginousà


  • Scarlatiniformà
  • Dermatitis with infection
  • Papular acrodermatitis
  • R/O syphilis, drug
  • LCH, infected seborrheic dermatitis
  • Scarlet fever, Kawasaki syndrome, Staphy, viral exanthem
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For some reason
Strep likes this site
 in these patients.
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DDx?
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same process…different color
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….DDx?
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Papular acrodermatitis…DDx?
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Vesiculopustular?
  • Groupedà
  • Disseminated
  • Tzanck (+) à


  • Tzanck (–) à
  • Mucous
  • membraneà


  • HSV, H Zoster


  • VZV, disseminated HSV
  • SJS, TEN, SSSS
  • Not in SSSS
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Reactive Erythema?
  • Morbilliformà



  • Urticariaà
  • Scarlatiniformà
  • Sweet syndromeà
  • Annular erythemaà
  • Viral, drug, Kawasaki, CTD, malignancy
  • Same
  • Same
  • Idio, malignancy
  • Lyme disease, CTD, other
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Persistent urticaria without itch…

  • …think vasculitis


  • Collagen vascular disease
  • Henoch Schonlein purpura
  • Drug reaction
  • Infection
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Purpura?
  • Palpableà






  • Non palpableà
  • Vasculitis
  • HSP, viral, drug, CTD, sepsis(bacterial,
  • fungal, RMSF)


  • Purpura fulminans (DIC), drug, viral
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Chronic Fever?
  • General health, growth, development?
  • Loss of landmarks?
  • Loss of weight?
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Clinical worries…
  • R/O collagen vascular disease
  • R/O malignancy
  • R/O inflammatory bowel disease
  • R/O chronic inflammatory skin disease
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Connective Tissue Disease
  • Rheumatic fever
  • Systemic lupus erythematosus
  • Dermatomyositis
  • Scleroderma
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Special Considerations
  • Erythroderma-total body red and scaly
  • Cutaneous findings in malignancy
  • erythroderma
  • Sweet syndrome
  • pyoderma gangrenosum
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When all else fails, ask your dermatologist, but make it a useful consult…
  • Give pertinent history
  • Include drug exposures
  • Describe the pattern, organization, etc.
  • And only then the morphology