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The Dermatopathology Laboratory at John Hopkins is a leading center for the study of skin conditions-both inflammatory dermatoses and tumors. The lab is known in particular for its expertise in the study and diagnoses of high-risk tumors including melanoma. Frequently consulted regarding classification of "atypical moles/dysplastic nevi," the laboratory offers a clinicopathologic approach to inflammatory conditions and gives differential diagnoses in clinical language.

With extensive experience, processing more than 20,000 cases each year, the Dermatopathology Laboratory at Johns Hopkins can provide accurate diagnoses and second opinions as well as sound recommendations for treatment management.

For further information, please call 410-955-3484.

Basic Research Programs

- Basic research in autoimmunity and autoimmune bullous disease
- Role of Langerhans cell in cutaneous immunity
- Chemokine research in atopic dermatitis
- Oncogenes
- Keratin biology research
- Classical conditioning in pharmacotherapy of psoriasis
- Chemoprevention/chemoprotection of skin cancers
- Development of small molecule inhibitors as targeted therapies for melanoma
- Molecular characterization of cutaneous T cell lymphoma and development of   diagnostic/prognostic algorithms
- Epidemiology of skin cancers
- Mouse models of basal cell carcinoma using K17 promoter transgenes and   development of targeted therapies

Translational Research

Integrating the diverse aspects of these research activities is central to the department's goal of identifying the mechanisms of cutaneous disease at the molecular level. The information gleaned from basic research, including gene array, will impact translational and applied research activities. Translational studies on atopic dermatitis, recombinant interleukin 12 in cutaneous T cell lymphoma, new Lamisil treatment protocol in onychomycosis and efalizumab in psoriatic arthritis are a few of the many translational studies underway.